hard painful bumps on muscles or tissue?

O.k.  there are 3 so far, does anyone else have painful bumps and lumps on the muscles? (can only tell by feeling them) mostly in thighs and arms?  And if so, do you know what they are?

CherylS's picture

CherylS

07/15/2009

Hi Janice, My husband has been experiencing lumps and bumps in the his upper inner thigh. At the same time the lymph nodes in this area (groin) are enlarged and red, even after the other lumps go away. He has been on different anti-biotics but it always comes back. He is on a new antibiotic now and, if this doesn't help, they are going to perform a biopsy. I'm not sure if this is connected to his MELAS or not??

janice's picture

janice

07/17/2009

Hi Cheryl, I would think it is related to the MELAS, or at least Mito. There are 5 or 6 people with Mito with this. I have had swollen lymp nodes in same area, in the past.??? Anti-biotics never did anything for it, (or the bumps.) If they are going to do a biopsy, i would be so grateful, if you would be willing to share the results. (A SMALL STEP FOR MAN, A BIG STEP FOR MANKIND!) HA. Did he have any luck with the electolytes?
beck7422's picture

beck7422

07/18/2009

I had fatty tumors that grew on my back (Lipomas) that were causing me a ton of pain. I hate them removed and the pain went away. I occassionally get more of them, but deep tissue massages seem to help break them apart. The ones that grew real big couldn't be broken apart and seemed to be pressing against pressure spots on my back triggering pain bursts which caused me to fall all the time.
janice's picture

janice

07/19/2009

Hi Beck, I am glad to see that works for you. I have been doing the deep tissue massage for at least 15 years now, and i have hundreds of them, so that hasn't worked for me. If it is (painful) fat deposits or lipomas, then perhaps not converting fats properly could play into it??? Another mito mystery?? They are not noticeable to see, only to touch, and they don't move. I have had a lipoma before, and it was different than these.???? The doctor didn't think they were lipomas??? Who knows?
arktjk's picture

arktjk

07/20/2009

Well, I have "bumps" in my upper back and shoulder muscles for years, I assume related to the melas, kind of like what fibromyalgia people have. The feel like muscle knots, but not lymph nodes. When they are more prominent, then more pain. Sometimes I have someone push on them real hard, but most of the time use a heating pad. Massages make the situation more painful for me. If it gets real bad and causes pain up into the neck and pinches a nerve, then I use a pain pill. Maybe this information is completely off base from the original question.
janice's picture

janice

07/21/2009

Absolutely not off base.I think we are talking about the same thing. They are pretty much all over really. They just vary in sizes. Some feel like peas, some like marbles, then, the odd small egg.ha)But they hurt like heck! ....and i agree the massage hurts me also, but without it i can't stop those shooting pains into head, and don't feel i would be mobile today. ( i can't take pain meds.) ( i think alot of us were previously diagnosed with fibramyalgia, before mito) Has anyone ever had theirs biopsied? That's 5/6 of us that have MELAS and the bumps. Connection???
cellolover's picture

cellolover

07/24/2009

Janice, I'm pretty sure that whatever I have isn't MELAS and I've never had bumps like that. It seems reasonable to think that it is at least more common with people who have MELAS.
beck7422's picture

beck7422

07/28/2009

Lipomas or fat deposits, they are supposedly COMMON in the population. Although small lumps that may go away with time are the most common. Many women have them in their breasts as they age. Big ones are less common. You can see the big ones (egg size or larger). If they are big enough to see, then they are probably too big to break apart with a massage or your body to easily break them apart. Those are better off being removed. They are usually biopsied to check for Cancer, but are rarely cancerous.
janice's picture

janice

07/28/2009

Arktjk, If you google "Fatty oxidation disorders" it may explain them more. My muscle biopsy says some "paracrystalline inclusions". I am thinking (my own opinion at this point)is that it is connected to fat that can't be oxidized, so it crystalizes.?? Vitamin E overloaad can also be a cause it mentions. ??
janice's picture

janice

08/03/2009

I found out what the LUMPS AND BUMPS are: "Paracrystalline inclusions" are indicative of mitochondrial dysfunction. The challenge is determining if an individual has mitochondrial dysfunction relative to PRIMARY mitochondrial disease or SECONDARY to another disease process. FOD's can be very "tricky" to sort out as they also can be primary or secondary.(cut and posted from lauras e-mail)A diet with high complex carbs, and protien, with LOW fat, is what they reccomend.I was surprised to learn that undiagnosed high blood pressure and joints that are sore and creek are listed symptoms of an F.O.D.
CherylS's picture

CherylS

08/16/2009

After being on an antibiotic for 1 month, and also being treated with antifungal meds, my husband's lumps and bumps cleared up for the most part. The doctor said he didn't think it was related to the MELAS and said to call them if the issue returns so.... no biopsy for now.