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Mitochondrial Disease News


Screening platform reveals compounds that protect neuronal mitochondria

Researchers have developed a screening system and identified a set of compounds that protect neuronal mitochondria in mice. A novel screening platform has been developed by researchers which has...


MDA Awards Venture Philanthropy Funding of More Than $1M to AavantiBio to Develop Gene-Targeting Therapy for Friedreich’s Ataxia

MVP is MDA’s drug development program, which is exclusively focused on funding the discovery and clinical application of treatments and cures for neuromuscular disorders. MVP evaluates and makes targeted...


UCP2-induced hypoxia promotes lipid accumulation and tubulointerstitial fibrosis during ischemic kidney injury

Abstract Mitochondrial dysfunction leads to loss of renal function and structure; however, the precise mechanisms by which mitochondrial function can regulate renal fibrosis remain unclear. Proximal tubular cells (PTCs)...


Caregivers Need Care, Too

STRATEGIES FOR CAREGIVING, ESPECIALLY WHEN A FAMILY MEMBER IS HOSPITALIZED: I was recently brainstorming ideas with other rare disease columnists about how to support someone admitted for a long...


Movement as medicine

A basic article on why exercise: Exercise is good for you. That’s hardly news: People who exercise tend to have longer, healthier lives. But until recently, researchers have tallied...


Mitochondria are the ‘canary in the coal mine’ for cellular stress

Illustration of mitochondria (stock image). Mitochondria, tiny structures present in most cells, are known for their energy-generating machinery. Now, Salk researchers have discovered a new function of mitochondria: they...


Know thy mitochondria: Autoimmunity to organelles and their DNA

VDAC1 oligomerization forms a pore for mtDNA. Credit: Jeonghan Kim et al. National Heart Lung and Blood Institute, Bethesda, MD The immune system uses its mitochondria to self-stimulate innate...


Stealth BioTherapeutics Presents Data for Elamipretide on Cardiac Function in Barth Syndrome

New data from open-label extension portion of TAZPOWER study demonstrated improved cardiac function BOSTON, Oct. 17, 2019 /PRNewswire/ — Stealth BioTherapeutics ( MITO ), a clinical-stage biotechnology company focused...


Stealth Biotherapeutics Shares Promising Data from Mitochondrial Myopathy Trial

July 19, 2017 Recently, at the 2017 UMDF Mitochondrial Medicine Symposium, Stealth BioTherapeutics shared very encouraging results from its second clinical trial for primary mitochondrial myopathy, the MMPOWER-2 study....


MitoAtion, the Foundation for Mitochhondrial Medicine and UMDF Jointly Authored Editorial

MitoAction, the Foundation for Mitochondrial Medicine and UMDF have jointly authored an editorial that was sent to major newspaper outlets across the United States. It is our hope that...