Fatigue Russell Weller Mar 13, 2023 The overall feeling of tiredness or lack of energy. It is not the same as simply feeling drowsy or sleepy. Being fatigued means having no motivation or energy. Related Articles: COVID-19: Mitochondria’s Pivotal Role in COVID-19.Glossary: Crohn’s DiseaseGenetic treatment plus exercise reverses fatigue in mice with muscle wasting diseaseHow is Mitochondrial Disease Treated?On the Wings of Hope