Jonathan Mordis, Houry Lepedjian and Jennifer Kmetich join me from Chemistry Rx. As experts in the preparation of customized medications for patients with rare disorders, they have expertise in compounding formulations for MitochondrialRelated to the mitochondria. Disease and they join me for a discussion about everything compounding.
EPISODE HIGHLIGHTS
What is a compounding pharmacy?
When you utilize a retail pharmacy, you have access to commercially available medications with standardized dosages that cater to most patients. A compounding pharmacy has the opportunity to create unique doses and dosage forms for different patients where a one-size-fits-most approach doesn't work for treatment. As a compounding pharmacy, we have access to the active ingredients in medications and put them into differing doses and forms for a range of patients and diseases.
Why would a mito patient use a compounding pharmacy?
When it comes to mito cocktails, everyone's body is different, and as it relates to mitochondrial disease and metabolic conditions, being able to individualize treatments is key to treating these conditions. It's crucial to customize mito cocktails to each patient's clinical genotype and phenotype- the way their genes present in genetic testing, physically and clinically. Different mutationsgenetic variant, genetic change require unique combinations and amounts of the ingredients that go into a mito cocktails and they all work together to compensate for a lack of specific metabolites, which is generally in a higher dose than what's available over the counter.
How does a patient get started if they want to utilize compounding services through Chemistry Rx?
The prescriber will send the prescription to us and a nurse from our clinical team will reach out to the patient to let them know we received it and we're working on the authorization process. They'll gather information about insurance, medications, dietary restrictions, and any personal preferences we should take into consideration. Throughout the process, we welcome patients to reach out about any part of the process, including insurance authorizations and claim appeals. Once a mito cocktail has been customized for a patient, it will be shipped overnight on ice as frequently as needed, before the last dose is complete.
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