The severity of mitochondrial disease symptoms is different from person to person. The most common symptoms are:
• Poor growth and failure to thrive (in children)
• Loss of muscle coordination, muscle weakness and pain, low tone, exercise intolerance • Neurological problems, seizures
• Autism, autistic spectrum, autism-like features
• Visual and/or hearing problems
• Developmental delays, learning disabilities
• Movement disorders
• Heart, liver or kidney disease
• Gastrointestinal disorders, including severe constipation, diarrhea, swallowing difficulty, repeated vomiting, cramping, reflux
• Diabetes
• Increased risk of infection
• Neurological issues, including difficult to treat seizures, migraines, and stroke or stroke like events
• Thyroid and/or adrenal dysfunction
• Autonomic dysfunction (may affect the functioning of the heart, bladder, intestines, sweat glands, pupils, and blood vessels
• Respiratory issues
• Lactic acidosis (the buildup of lactate in the body, which results in an excessively low pH in the bloodstream)
• Neuropsychological changes characterized by confusion, disorientation, dementia, and memory loss